Mokhoa oa ho khetha Serotonin Reuptake Inhibitors (SSRIs) o sebetsa joang
Reuptake ke tšobotsi ea bohlokoa ea meriana ho utloisisa hore na u na le bothata ba botho ba borderline (BPD) kapa bothata leha e le bofe ba bophelo bo botle ba kelello. Hobane'ng? Hobane meriana e mengata e sebelisoang ho sebetsana le mathata a bophelo ba kelello e sebetsa ka ho fetola li-neurotransmitters tse itseng tse bokong. Reuptake ke karolo ea bohlokoa ea ts'ebetso ena.
Li-neurotransmitters ke manģosa a lik'hemik'hale a fanang ka tsela ea ho fetisa lipontšo tse hlahisoang ke methapo ea methapo (neurons) ho pholletsa le synaps es (libaka pakeng tsa lisele) ho tloha seleng e 'ngoe ea methapo ho ea ho e' ngoe.
Reuptake ke se etsahalang ka mor'a hore pontšo e fetisoe: "Neurotransmitter," mosebetsi "oa eona o phethiloe, e khutlisetsoa hape ka seleng e neng e le lokollile pele.
Ke Hobane'ng ha Reuptake e le ea Bohlokoa Phekolo ea ho Tepella Maikutlo ho BPD?
Ho tetebela maikutlo ka BPD le mathata a mang a bophelo ba kelello ho amahanngoa le maemo a tlase a lik'hemik'hale tse ling tsa boko, ho akarelletsa serotonin, dopamine le norepinephrine.
Haeba o na le BPD mme o noa meriana ho phekola ho tepella maikutlong (ka mantsoe a mang, motho ea nang le bothata ba ho tepella maikutlo), u ka 'na ua nka serotonin reuptake inhibitor kapa SSRI. Mokhoa o tloaelehileng oa ho imeloa kelellong, hangata li-SSRI li sebelisoa ho tšoara batho ba nang le BPD ka ho fokotsa matšoao a tekanyo le ho tepella maikutlong.
SSRI e eketsa lenane la serotonin ea methapo ea pelo ka boong, joalokaha u se u ntse u elelloa, e liehisa ho tsosolosoa ha eona ka lisele tse li fetisitseng. Ka lebaka leo, li-serotonin tse phahameng ho feta tse tloaelehileng li setseng ho potoloha bokong.
Ho eketsa boholo ba serotonin bokong bo bonahala ho thusa lisele tsa boko bo buisanang, tse thusang ho phahamisa khatello ea maikutlo le ho ntlafatsa maikutlo. Serotonin e 'nile ea bitsoa "lik'hemik'hale" tsa tlhaho tsa' mele hobane li hlahisa maikutlo a boiketlo.
Joalokaha u ka bona, SSRIs ha e thuse 'mele hore o hlahise serotonin e mengata.
Ho e-na le hoo, ba thusa 'mele ho potoloha serotonin e ngata.
Mehlala ea SSRIs
Mona ke mabitso a SSRI a fumanehang ho ngaka ea hau ho ngola:
- Citalopram (Celexa)
- Escitalopram (Lexapro)
- Fluoxetine (Prozac, Sarafem)
- Fluvoxamine (Luvox)
- Paroxetine (Paxil, Paxil XR, Pexeva)
- Sertraline (Zoloft)
Lentsoe la Temoso ea Serotonin Syndrome
Mokhoa oa reuptake o boetse oa phetha karolo ea boemo bo sa tloaelehang empa bo kotsi, bo etsahalang ha motho a nka meriana e mabeli e eketsang boemo ba serotonin 'meleng. Sena se ka fella ka maemo a kotsi a serotonin bokong.
Meriana eo u sa lokelang ho e nka hammoho e kenyeletsa:
- Ho tepella maikutlo, ho akarelletsa le SSRIs
- Mahlaba a mang kapa meriana e bohloko
- Meroho e tlatsetsa setopo sa St. John's
Matšoao a lefu la serotonin a kenyeletsa:
- Lebelo la pelo le potlakileng
- Ho tšoenyeha
- Ho tsitlella
- Ho hloka botsitso
- Pherekano
- Ho rohakana
- Litlhoko
- Ho hloka botsitso
Haeba o na le matšoao ao, fumana thuso ea bongaka hang-hang.
Lefu la Serotonin le ka etsahala ha o qala ho nka meriana e matlafatsang serotonin kapa ha u eketsa lethal dose.
Lefu la Serotonin ha lea tloaeleha, haholo hobane lingaka li hlokolosi haholo ka ho fana ka meriana e ka e bakang. Leha ho le joalo, kaha lefu lena le kotsi haholo, FDA e botse baetsi ba mefuta ena ea meriana hore ba behe mangolo a temoso ho bona ba ka u hlokomelang kotsi ena.
Lisebelisoa:
"Kamoo SSRIs e sebetsang kateng." Healthline.com (2013).
"Ho tepella maikutlo (bothata bo boholo ba ho tepella maikutlong): serotonin reuptake inhibitors (SSRIs) e khethollang." Mayo Clinic (2013).
"Serotonin Syndrome." Laebrari ea Sechaba ea Meriana ea US. MedlinePlus (2016).