Lisosa, tlhokomelo le kalafo
Serotonin Syndrome ke boemo bo sokelang bophelo bo bakoang ke maemo a phahameng a serotonin tsamaisong ea motho. Boemo bona bo ka tlisoa ke tšebeliso ea lithethefatsi "serotonergic", tse kenyelletsang mefuta e 'maloa ea li-anti-depressants, tse kang SSRIs (selective serotonin reuptake inhibitors) joaloka Paxil le Celexa , tricyclics joaloka amitriptyline le trimipramine, le MAOI (monoamine oxidase inhibitors) joaloka Nardil le Parnate.
Lintho tse ling tse ka kenyang letsoalo la serotonin li kenyeletsa setho sa St. John's , cocaine, L-tryptophan, lithium, amphetamines, ecstasy le LSD.
Ho phaella moo, lithethefatsi tse ling tse seng tsa kelello li ka ama boemo ba serotonin maling. Ka lebaka lena, ke habohlokoa hore lingaka tsohle tsa hau tse fanang ka meriana kamehla li tseba meriana eohle le li-supplement tseo u li nkang hona joale.
Lithethefatsi tsena le lisebelisoa tsena li ama serotonin ea methapo ea kutlo ka tsela e itseng. Tse ling li thibela batho ba nang le methapo ea meriana; thibelo e 'ngoe ea boithaopo ; tse ling li liehisa ho senyeha ha serotonin; ba bang ba eketsa ho lokolloa ha serotonin (bakeng sa mohlala, bona Lithethefatsi tsa Seterateng le BP: Ecstasy ). Mefuta ea batho ba bang ka tlhaho e lieha ho feta kamoo e tloaelehileng kateng ho sebelisa metabolizing serotonin. Nolan le Scoggin ba tlaleha hore bakuli ba nang le lefu la vascular ba kotsing e kholo ea lefu la serotonin. (Bona Mabitso a Brain bakeng sa tlhaloso e nolofalitsoeng ea tsela eo tse ling tsa mesebetsi ena li sebetsang ka eona.)
Hoo e batlang e le bothata bohle ba ho tepella maikutlo ho na le temoso ea hore bakuli ba lokela ho emela bonyane libeke tse peli (ka linako tse ling ho feta) pakeng tsa ho fetoha pakeng tsa lithethefatsi tsa mofuta oa MAOI le mofuta o mong oa ho imeloa kelellong (ka tsela efe kapa efe). E 'ngoe ea mabaka a ka sehloohong a sena ke kotsi ea ho ba le mefuta e' meli ea lithethefatsi tsamaisong ea motho e ka lebisang serapong sa serotonin.
Prozac (fluoxetine) ka ho khetheha e nka libeke tse 'maloa hore li ntšoe ka ntle ho' mele.
Matšoao
Matšoao a tloaelehileng a lefu la serotonin a akarelletsa:
- Ho ts'oaroa ka tšohanyetso kapa ho tsosoa
- Ho phahamisa kapa ho ba le bothata
- Phello e nyenyane kapa e potlakileng
- Feberu
- Hlooho ea hlooho
- Ho tšoenyeha
- Boima ba mesifa
- Pherekano
- Ho hloka botsitso
- Ho fufuleloa ho feteletseng
- Moferefere
- Tšebelisano e mpe
- Ho phefumoloha kapele
- Ho otlolla pelo ho sa tloaelehang
- Khatello ea mali e phahameng
- Ho thothomela
Ho na le boloetse bo bong bo amanang le lithethefatsi, lefu la neuroleptic malignant syndrome (NMS), le nang le matšoao a tšoanang le a serotonin. Ha lingaka li hlahloba mokuli ea bontšang matšoao ana, ke habohlokoa hore ba tsebe ka hohle kamoo ho khonehang historing ea meriana ea mokuli. Lebaka ke hore lefu la serotonin le atisa ho hlaha ka potlako ka mor'a ho qala meriana ea thaba, ha NMS e atisa ho nka khoeli ho bontša.
Phekolo
Mokha oa pele oa phekolo ke ho khaotsa lithethefatsi tsohle tse amang serotonin. Benzodiazepines e ka 'na ea thusa ho kokobetsa matšoao a mesifa,' me phekolo e ka tšehetsang e ka 'na ea hlokahala bakeng sa maemo a kang ho tepella maikutlo. Lithethefatsi tse sebetsang ka ho toba khahlanong le serotonin le tsona li ka ba molemo.
Maemong a mangata, matšoao a theoha ka potlako hang ha sena se etsoa 'me mokuli a hlaphoheloa ka botlalo.
Leha ho le joalo, ho lokela ho totobatsoa hore lefu la serotonin le ka bolaea, kahoo ke habohlokoa ho batla thuso kapele haeba uena kapa moratuoa a lokela ho ba le matšoao a mangata ka holimo ka morao ka mor'a ho qala mohatelli o mocha oa khatello ea maikutlo kapa ho fetoha ho tloha ho e mong ho ea ho o mong.
SSRI Discontinuation Syndrome
Ho lokela ho hlokomeloa hore tse ling tsa matšoao a tšoanang a boletsoeng ka holimo li ka boela tsa etsahala ha motho a ema hang-hang a noa motho ea itšireletsang kapa a mo fokotsa ka potlako. Ho tsuba, ho hloohoa ke hlooho, ho tšoha-joaloka maikutlo, ho sebelisana hampe, ho tsieleha le ho sithabela maikutlong ke tse ling tsa litšobotsi tse tloaelehileng ho li-syndromes.
Bona SSRI Discontinuation Syndrome bakeng sa ho sheba ka botebo boemo boo.
> Litlhaloso:
> Nolan, S., le Scoggin, JA "Serotonin Syndrome: Ho Amoheloa le Tsamaiso." US Pharmist 23: 2. http://www.uspharmacist.com/oldformat.asp?url=newlook/files/feat/acf2fa6.htm.
> Gomersall, C. "Serotonin Syndrome." July 2006
> HealthyPlace.com. "Monoamine > Oxydase > Inhibitors (MAOIs)."