Lithethefatsi Tsena ha li Sebetse Haholo Joalokaha li ne li le Nako Hang
Li-barbiturates ke sehlopha sa lithethefatsi tse fumanoang mobung oa barbituric o etsang lintho tse nyahamisang tsamaiso ea methapo ea mantlha . Lithethefatsi tsena li sebelisoa e le lits'ebetsong kapa li-anesthetics 'me li na le monyetla oa ho ba lemalla. Ba na le bothata hobane ha ho na phekolo e ntle ea ho fokotsa ho fetela ha barbiturate.
Tšebeliso e ka sehloohong ea barbiturate lekholong la bo21 la lilemo e 'nile ea e-ba ho ipolaea ka thuso ea lingaka (moo ho buuoang ka mekhoa e joalo).
Histori ea Barbiturates
Mofuputsi oa Lejeremane Adolph von Baeyer e bile eena oa pele oa ho etsa li-acbituric acid. Barbital (Veronal) e ne e le barbiturate ea pele 'me e ne e sebelisetsoa merero ea bongaka ka 1903. Li-barbiturates li ne li atisa ho sebelisoa ho sebetsana le khatello, matšoenyeho le ho robala, empa tšebeliso ea bona ea ho phekola matšoao a joalo ha aa ka a amoheloa ka lebaka la kotsi ea ho fetela holimo le tlhekefetso.
Tlaleho e na le taba ea hore lebitso lena la lithethefatsi le tsoa ho letsatsi leo Baeyer le basebetsi-'moho le eena ba entseng hore li sibolloe: Kamoo ho bonahalang kateng ba ile ba ea keteka seo ba se fumaneng tafoleng ka letsatsi la mokete oa St. Barbara.
Benzodiazepines e kentse boholo ba libaka tsa barbiturate litšebelisanong tse ngata tsa bongaka.
Liphello tsa Barbiturates
Liketso tsa pharmacological tsa barbiturates li akarelletsa ho tepella maikutlo mokhoeng oa pelo, mesifa le boreleli. Lithethefatsi tsena li boetse li ama CNS ka litsela tse ngata tse fapaneng 'me li ka hlahisa liphello ho tloha ho sedation ho ea ho coma ho itšetlehile ka tekanyo.
Mokhoa o fokolang oa li-barbiturates o ka fokotsa matšoenyeho 'me oa fokotsa tsitsipano, ha tekanyo e phahameng e ka fokotsa lebelo la pelo le khatello ea mali.
Li-barbiturate li na le mathata a mangata, ho akarelletsa:
- Ho ka 'na ha e-ba le likamano tse kotsi le lithethefatsi tse ling
- Ho hloka polokeho le khetho
- Tloaelo ea ho theha botšepehi, mamello, tlhekefetso le ho tlosoa
- Ho hloka phekolo e atlehileng bakeng sa ho feta tekano
Mehlala ea Barbiturates
- Amobarbital: Ka tloaelo ho bitsoa "sodium amytal", barbiturate ena e ile ea tsebahala e le 'nete ea seramu kaha e ile ea sebetsa ha e fuoa lintlha tse ling nakong ea lipotso. Le ha e hlile e qobella batho ho bua 'nete, amobarbital e ka liehisa tsamaiso ea methapo ea mantlha e le hore ho be thata haholoanyane ho tsepamisa mohopolo. Khopolo ea hore motho e mong o botsa potso ha a le tlas'a tšusumetso ea amobarbital e ke ke ea e-ba bonolo ho nahana ka karabo ea bohata, e hlokang ho tsepamisa maikutlo ho feta ho bua 'nete feela.
- Butalbital: barbiturate ena e khutšoanyane e ne e atisa ho sebelisoa ho tšoara hlooho ea hlooho ea migraine, hangata e kopantsoe le acetaminophen, aspirin le caffeine. E ne e rekisoa tlas'a mabitso a brand Fiorinal le Fioricet. E boetse e sebelisitsoe e le sedative le anesthetic. E ne e rekisoa tlas'a mabitso a brand Fiorinal le Fioricet. E boetse e sebelisitsoe e le sedative le anesthetic.
- Phenobarbital: Barbiturate ena e ne e sebelisetsoa ho tšoaroa ke ho tšoaroa ke bana ba banyenyane, ka lebaka la katleho ea eona joaloka anticonvulsant. Hape e 'nile ea sebelisoa ho tšoara ho tšoenyeha, ho tlosoa lithethefatsi (haholo-holo ho tsoa ho tse ling tsa barbiturates) le joaloka thuso ea boroko.
- Secobarbital: Ho rekisoa United States e le tšimoloho ea Sechaba ka 1934, lithethefatsi ena e ne e le thuso e fanoang ka ho fetisisa ea boroko. Ke lithethefatsi tse sebelisoang ka ho fetisisa ho ba ipolaeeng ba thusang lingaka US
- Pentobarbital: E sebelisoa e le sethoathoa sa liphoofolo liphoofolong, sethethefatsi sena se neng se sebelisoa ho sebetsana le ho tšoaroa ke mafu le ho ferekanya ho na le phapang e tsotehang ea ho ba lithethefatsi tse khethiloeng tse sebelisetsoang ho bolaoa ha naha US
Litlhaloso tse ling tsa Psychology: The Psychology Dictionary
> Mehloli:
> Ilangaratne, NB; Mannakkara, NN; Bell, GS; Sander, JW "Phenobarbital: ha e sebetse." . Bulletin of the World Health Organization . Dec. 2012
> Maiser >, S., le al "Hospice le Meriana ea tlhokomelo ea tlhokomelo ea tlhokomelo ea tlhokomelo ea meriana mabapi le tšebeliso ea Palliative Sedation," Journal of Palliative Medicine May 2017